Molecular, Cellular and Systemic Physiology Courses | 2024-2025 Graduate Catalog | SIU

A-B sequence. Laboratory dissection of the human body with lectures as needed. Primarily for students majoring in physiology, biological sciences, anthropology or pre-medical fields. Prerequisite: PHSL 301. Enrollment by consent of instructor. Lab fee: $20.

Credit Hours: 5

A-B sequence. Laboratory dissection of the human body with lectures as needed. Primarily for students majoring in physiology, biological sciences, anthropology or pre-medical fields. Prerequisite: PHSL 301. Enrollment by consent of instructor. Lab fee: $20.

Credit Hours: 5

This course is intended to provide life sciences students with an introduction and understanding of mammalian tissues with a strong emphasis on human anatomy. The course utilizes self-directed and problem-based learning strategies employing on-line resources including virtual microscopy. By completing this course, successful students should 1) be familiar with the organization, structure, and appearance of mammalian tissues; 2) be able to recognize and identify tissues from all major mammalian organs; and 3) be able to describe the relationship between tissue conformation and organ function. Prerequisites: BIOL 211 and PHSL 301 with grades of C or better.

Credit Hours: 4

Examines basic principles of pharmacology (pharmacokinetics) and the action of various classes of drugs on living organisms. Drug classes covered include those affecting most organ systems of the human body, such as the nervous, cardiovascular, gastrointestinal and renal systems as well as drugs used for antibiotic and cancer chemotherapy. Three lectures per week. Prerequisites: PHSL 310 or PHSL 410A,B, CHEM 340 and CHEM 341 (or equivalent) with grades of C or better.

Credit Hours: 3

Examines basic principles of pharmacology (pharmacokinetics) and the action of various classes of drugs on living organisms. Drug classes covered include those affecting most organ systems of the human body, such as the nervous, cardiovascular, gastrointestinal and renal systems as well as drugs used for antibiotic and cancer chemotherapy. Three lectures per week. Prerequisites: PHSL 310 or PHSL 410A,B, CHEM 340 and CHEM 341 (or equivalent) with grades of C or better.

Credit Hours: 3

(Same as ANS 426, ZOOL 426) Comparison of mechanisms influencing hormone release, hormone biosynthesis, and the effects of hormones on target tissues, including mechanisms of transport, receptor kinetics, and signal transduction. Prerequisites: PHSL 310 or ANS 331 or ZOOL 220 with a grade of C. Laboratory/Field Trip fee: $15.

Credit Hours: 3

This course will examine the molecular and cellular aspects of physiology in the context of human pituitary and neurological genetic disorders. Topics include experiments and model systems used to examine the regulation of gene expression, signaling pathways, protein activities, and cellular functions that underlie these disorders. Prerequisites: BIOL 306 or CHEM 350 & 351 with minimum grade of C or better.

Credit Hours: 3

(Same as ZOOL 433) Variations of the physiological processes in animal phyla, comparison with human physiology, and review of basic physiology principles and comparative aspects of mechanism and function. Prerequisite: BIOL 211, BIOL 212 & BIOL 213 or PHSL 310 with a grade of C or better.

Credit Hours: 3

Biomathematics, biomechanics and biotransport. Three lectures per week. Prerequisites: MATH 141 or 150; PHSL 310; PHYS 203 A&B and 253 A&B or PHYS 205 A&B and 255 A&B. May be taken in B,A sequence with consent of instructor.

Credit Hours: 3

Bioelectrics and bio-optics applied to physiological problems. Three lectures per week. Prerequisites: MATH 141 or 150; PHSL 310; PHYS 203 A&B and 253 A&B or PHYS 205 A&B and 255 A&B. May be taken in B,A sequence with consent of instructor.

Credit Hours: 3

(Same as WGSS 449) Advanced, comprehensive course intended to supplement and expand the critical examination of topics covered in PHSL 320, Reproduction and Sexuality. The objectives of this class are to examine the physiological and behavioral basis of human reproduction and sexuality. Examining how humans reproduce from a physiological perspective including all aberrations and clinically relevant dysfunctions, as well as, the spectrum of human sexual behaviors including typical and atypical sexual behavior, paraphilias and diversity of human relationships. Prerequisite: PHSL 320.

Credit Hours: 3

Lecture course designed to introduce the student to the theory and principles of electron microscopy. Two lecture hours per week. Restricted to senior standing or permission of instructor.

Credit Hours: 2

Diagnostic and therapeutic modalities related to engineering. Cardiovascular, neural, sensory and respiratory instrumentation. Special approval needed from the instructor.

Credit Hours: 3

Study of the temporal aspects of diverse physiological and behavioral functions which possess diurnal and sectional periodicity. Species covered will include many eukaryotic organisms including plants, but will mainly stress mammals. Oscillations in sleep-wake cycle, locomotion, reproduction, hormonal secretion and numerous other processes will be explored. In addition, the effects of biological clocks in humans and the effect of jet lag and depression will be examined. Prerequisite: PHSL 310.

Credit Hours: 3

Goal of the journal club is to discuss current primary journal articles about cancer, often with an emphasis on ovarian cancer. Each semester a theme is selected to guide selection of articles. Grade is based on: 1) presentation; 2) participation; 3) short essay on each journal article that is discussed. Each student presents at least one journal article per semester and is expected to participate in the discussion of each paper that is presented. Faculty and graduate students also present articles for discussion to provide examples of how to read and discuss primary scientific literature. Student will, with instructor approval, choose either 1 cr/hr for a research paper component for which they write a 10 page research paper reviewing current literature related to the journal club's theme for the semester or a different cancer theme as determined by the instructor, or select 2 cr/hrs for journal club participation as outlined above, or 3 cr/hrs for completing both course components. Prerequisite: PHSL 310 with a B or better or concurrent enrollment.

Credit Hours: 1-3

Presentation of research and current literature in physiology. Required of all graduate students in physiology. Course restricted to physiology graduate doctorate and graduate masters students only. Graded S/U.

Credit Hours: 1

Research areas and special topics requisite for conducting scientific research will be presented. Students will learn how to organize a talk, prepare slides, communicate effectively in an oral presentation, write a research proposal, design experiments, and write a curriculum vitae. Required of all graduate students in Molecular, Cellular, and Systemic Physiology.

Credit Hours: 2

Advanced Human Neuroanatomy with Lab (4 hours) examines the detailed structure of the human nervous system, linking structure to function at both the clinical and neurobiological level. The overall objective of the course will be a three-dimensional understanding of nervous system structure and organization, based upon anatomical connections, functions, and diseases. Graduate students will engage in literature reviews relevant to course material and submit final projects as approved by course instructors. Enrollment requires consent of the instructor. Students who have passed PHSL 402 are not eligible for enrollment. Lab fee: $25.

Credit Hours: 4

Embryology is the branch of anatomy that looks at the developmental events that occur prior to birth. This course is designed to provide a basic foundation in human embryology to graduate students who are interested in the biomedical sciences. In this course, we will explore human development from fertilization to birth. Our major focus will be on the morphological changes that take place during development, but we will also explore many of the underlying molecular mechanisms and relevant congenital anomalies. Students will review and discuss current literature relevant to each unit and complete final projects as approved by the course instructor. Approval of the instructor required for enrollment. Students who have passed PHSL 403 are not eligible for enrollment.

Credit Hours: 3

The main objectives of this course are to acquaint the student with the techniques and the equipment used in modern research laboratories and to provide instruction in the principles and practice of scientific experimentation. Restricted to Physiology (MCSP) graduate students only.

Credit Hours: 3

Physical and chemical organization and function in mammals, with emphasis on the human. Physiology of blood and circulation, respiration, digestion, metabolism, excretion, endocrines, sensory organs, nervous system, muscle and reproduction. Four lectures and one seminar per week. Seminar will consist of primary literature discussion and student presentation on areas covered in lecture. Principal lecturer for each of the area topics will lead discussion and assign the primary literature. May be taken in any sequence. Restricted to consent of department. Special approval needed from the instructor.

Credit Hours: 1-5

Physical and chemical organization and function in mammals, with emphasis on the human. Physiology of blood and circulation, respiration, digestion, metabolism, excretion, endocrines, sensory organs, nervous system, muscle and reproduction. Four lectures and one seminar per week. Seminar will consist of primary literature discussion and student presentation on areas covered in lecture. Principal lecturer for each of the area topics will lead discussion and assign the primary literature. May be taken in any sequence. Restricted to consent of department. Special approval needed from the instructor.

Credit Hours: 1-5

This online course is designed to introduce instructional theories and methods to students interested in teaching in the Life Sciences. It will provide coverage of methods of classroom instruction, management and assessment. The methodology of the course will include projects on lesson construction, online discussion boards of readings, and quizzes. Students should finish the course prepared to be competent in up-to-date methodology and strategies in critical teaching practices.

Credit Hours: 2

Advanced, comprehensive course examining the physiological and behavioral basis of human reproduction and sexuality. Topics include physiology and pathophysiology of the human reproductive system and normal and atypical sexual behavior. Course topics will include didactic presentations and problem-based lab discussions selected by the students selected from lecture or related topics. The class will meet three times weekly for didactic presentations and once a week for a three hour extensive discussion and presentation utilizing self-directed learning strategies and knowledge in a problem-based format, similar to that used in the medical school curricula. Special approval needed from the instructor.

Credit Hours: 4

This course will examine the molecular and cellular aspects of physiology in the context of human pituitary and neurological genetic disorders using the primary literature as the source of topics for oral presentations and discussions. Topics include experiments and model systems used to examine the regulation of gene expression, signaling pathways, protein activities, and cellular functions that underlie these disorders. Special approval needed from the instructor.

Credit Hours: 3

One one-hour lecture and one three-hour laboratory per week, designed to be taken concurrently with PHSL 530. Basic experimental procedures used in studies in cellular physiology.

Credit Hours: 2

Advanced concepts and techniques used in current studies in comparative physiology. Three lectures and one discussion period per week.

Credit Hours: 4

Survey of recent biophysical research with emphasis on historical development of current advances. Three lectures per week. Prerequisite: PHSL 440 or its equivalent.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Studies of current research and literature in various topic areas of physiology. One or more of the following list of topic sections will be offered each semester, so that each section will be available once every two or three years.

Credit Hours: 3

Laboratory course designed to provide experience in techniques for biological electron microscopy. Student, with the aid of the instructor, designs and carries out a project in transmission electron microscopy. Two three-hour laboratories per week. Prerequisite: PHSL 460 or special permission of instructor.

Credit Hours: 3

A detailed survey of human neuroanatomy. The course will include radiographic, cross-sectional and developmental anatomy of the nervous system. Dissection of the human brain will occur in general laboratory sessions. Three lectures per week.

Credit Hours: 3

(Same as PHRM 574) A detailed examination of the biochemical aspects of neuropharmacology with emphasis on neurotransmitters - their synthesis, storage, release and metabolism in the central and peripheral nervous system. Considerable emphasis is placed on major health research developments (both past and present) that influence how one studies the action of drugs on the nervous system. Prerequisites: PHSL 410A/B, and CHEM 350.

Credit Hours: 3

Designed to investigate and discuss the current research and historical aspects of the field of neuroendocrinology. In addition, designed to have students examine and evaluate current literature in the field and through discussion have them present their analysis of the research. One hour of lecture, one hour of discussion of textual material, one hour of multiple reports on library research. Prerequisite: PHSL 410A, B or equivalent, or an undergraduate/graduate endocrinology course, or consent of instructor.

Credit Hours: 3

Students will participate in the daily discussions of a medical education multimedia corporation. Emphasis will be on process and instructional design. Students will be supervised by team members in the production of commercial educational packages. Skills to be acquired include the ability to digitize images and sound, and to create a Power Point presentation on a topic of the student's choice.

Credit Hours: 3

Intended to be a "hands on" course which contributes significantly to the development of multimedia teaching materials for medical education. Students will be assigned to a project as part of a development team. Under supervision of the team leader, they will assist in software design, material preparation and assembly. Prerequisite: PHSL 581A.

Credit Hours: 6

The study of human anatomy through imaging techniques such as standard x-rays, computer assisted tomography (CT) and magnetic resonance imaging (MRI). The course will include individualized work with clinical specialists in a hospital setting for 1/2 day per week with times to be arranged. Restricted to graduate status, acceptance into anatomy certificate program. Graded S/U.

Credit Hours: 3

By special arrangement with the instructor with whom the student wishes to work. Graded S/U only.

Credit Hours: 1-4

The credit hours selected for this course registration will be determined by the major professor of the student. In a typical semester no more than six hours will be taken by a student except under special circumstances. Graded S/U only. Special approval needed from the instructor.

Credit Hours: 1-12

Research for thesis for Master's degree.

Credit Hours: 1-6

Research for dissertation for Ph.D. degree.

Credit Hours: 1-32

For those graduate students who have not finished their degree programs and who are in the process of working on their dissertation, thesis, or research paper. The student must have completed a minimum of 24 hours of dissertation research, or the minimum thesis, or research hours before being eligible to register for this course. Concurrent enrollment in any other course is not permitted. Graded S/U or DEF only.

Credit Hours: 1

Must be a Postdoctoral Fellow. Concurrent enrollment in any other course is not permitted.

Credit Hours: 1