Multidisciplinary Biomedical and Biological Sciences Courses | 2025-2026 Graduate Catalog | SIU

(Same as MICR 403) A survey of the more common bacterial, mycotic and viral infections of humans with particular emphasis on the distinctive properties, pathogenic mechanisms, epidemiology, immunology, diagnosis and control of disease-causing microorganisms. Three hours lecture. Spring semester. Prerequisite: MICR 301, or consent of instructor.

Credit Hours: 3

(Same as MICR 405) This course will be offered in Springfield only. A comprehensive course for health science professionals covering the biology, virulence mechanisms, and identification of infectious agents important in human disease and host-defense mechanisms. Clinical applications emphasized. Three hours lecture. Prerequisite: MICR 301, or consent of instructor.

Credit Hours: 3

(Same as MICR 406) Introduction to Mycology. This course will provide an overview of fungal diversity and taxonomy, fungal cell and molecular biology. Additionally, it will cover the ecological, economic, and historical impact of fungi on the environment, science, and society. Prerequisite: MICR 301 or consent of instructor.

Credit Hours: 3

(Same as MICR 421) Topics covered will include the genetic basis of the revolution in biotechnology, medical applications including genetic screening and therapeutic agents, industrial biotechnology and fermentation, and agricultural applications. Three hours lecture. Fall semester. Prerequisite: MICR 302, or consent of instructor.

Credit Hours: 3

(Same as MICR 423 and GEOL 423) The course will focus on the role that microorganisms play in fundamental geological processes. Topics will include an outline of the present understanding of microbial involvement of weathering of rocks, formation and transformation of soils and sediments, and genesis and degradation of minerals. Elemental cycles will also be covered with emphasis on the interrelationships between the various geochemical cycles and the microbial trophic groups involved. Prerequisite: MICR 301 and CHEM 210 and 211. Recommended: GEOL 220, 221 or 222.

Credit Hours: 3

(Same as MICR 425) Chemical composition, cellular structure, and metabolism of microorganisms. Fall semester. Prerequisite: CHEM 340 or CHEM 339.

Credit Hours: 3

(Same as MICR 453) Principles of molecular and cellular immunology. Particular emphasis is given to molecular mechanisms involved in activation and maintenance of the immune response at the basic science level. The role of the immune system in medical diagnostic procedures and in human health is also discussed. Spring semester. Prerequisite: MICR 403, or consent of instructor.

Credit Hours: 3

(Same as MICR 460) The genetic mechanisms and regulatory events that control gene transfer, lambda phage infection, recombination, and metabolic pathways including a brief introduction to bioinformatics, genome analysis and global regulatory functions. Three hours lecture. Fall semester. Prerequisite: MICR 301 and 302, or consent of instructor.

Credit Hours: 3

(Same as MICR 470) A consideration of the major groups of prokaryotes with special emphasis on their comparative physiology and ecology. Three hours lecture. Spring semester. Prerequisite: MICR 301, or consent of instructor.

Credit Hours: 3

Training in the interpretation of research and current literature in the biomedical and biological sciences. Format will include seminar presentations and/or Journal Club sessions.

Credit Hours: 1-16

Presentation and discussion of research and current literature in the biomedical and biological sciences. Format will include seminar presentations and/or Journal Club sessions.

Credit Hours: 1-16

The main objectives of this course are to acquaint students with the techniques and the equipment used in modern research laboratories and to provide instruction in the principles and practice of scientific experimentation. Students rotate through at least three research laboratories. Course is restricted to thesis M.S. and Ph.D. students in the Multidisciplinary Biomedical & Biological Sciences (MBBS) Graduate Program.

Credit Hours: 3

Embryology is the branch of anatomy that looks at the developmental events that occur prior to birth. This course is designed to provide a basic foundation in human embryology to graduate students who are interested in the biomedical sciences. In this course, we will explore human development from fertilization to birth. Our major focus will be on the morphological changes that take place during development, but we will also explore many of the underlying molecular mechanisms and relevant congenital anomalies. Students will review and discuss current literature relevant to each unit and complete final projects as approved by the course instructor. Approval of the instructor required for enrollment. Students who have passed PHSL 403 are not eligible for enrollment.

Credit Hours: 3

This course is designed to provide foundational knowledge in topics and concepts that are common to disciplines in biomedical and biological research. Basic skills training in experimental design and research methods will be acquired through lectures, workshops, assignments and through reading and reviewing scientific literature.

Credit Hours: 3

Seminar on social, professional, and scientific issues of interest to students planning a career in the biomedical sciences. Course focuses on development of professional writing, and approaches to professional school application.

Credit Hours: 1

Course covers advanced topics in biological and biomedical science. Understanding of biomedical science research and biological problem solving are emphasized. Course also focuses on preparatory strategies for professional school admissions examinations.

Credit Hours: 2

This course is intended to provide students with an understanding of mammalian tissues with a strong emphasis on human anatomy. The course utilizes self-directed and problem-based learning strategies employing on-line resources including virtual microscopy. By completing this course, successful students should 1) be familiar with the organization, structure, and appearance of mammalian tissues; 2) be able to recognize and identify tissues from all major mammalian organs, 3) be able to describe the relationship between tissue conformation and organ function, 4) be able to discuss methods for histological techniques, 5) be able to discuss troubleshooting for histological techniques and 6) be able to demonstrate critical thinking skills to understand how the altered structure and function of cells, tissues and organs may lead to pathology.

Credit Hours: 4

This course is an introduction to the concepts and practices of public health at the community, state, and national levels. The course addresses the philosophy, purpose, history, organization, functions, activities and impact of public health practice. The course also addresses a number of important health issues and problems facing the public health system. Special emphasis will be placed on the role of public health laboratory in public health practice. Discussion questions and case studies are integrated into the course, serving to stimulate student participation in gaining in-depth knowledge about real world public health issues and practice. Prerequisite: Bachelor's degree in Microbiology or other Biology, Chemistry, Physical Science.

Credit Hours: 3

Physical and chemical organization and function in mammals, with emphasis on the human. Topics include cell, molecular, excitable membrane, cardiovascular, respiratory, renal, neural, gastrointestinal, endocrine and reproductive physiology. Four lectures per week. Students will develop critical reasoning and understanding in subject areas through the reading and evaluation of current research literature. MBBS 511A and MBBS 511B can be taken in any sequence. Restricted to consent of department. Special approval needed from the instructor.

Credit Hours: 4

Physical and chemical organization and function in mammals, with emphasis on the human. Topics include cell, molecular, excitable membrane, cardiovascular, respiratory, renal, neural, gastrointestinal, endocrine and reproductive physiology. Four lectures per week. Students will develop critical reasoning and understanding in subject areas through the reading and evaluation of current research literature. MBBS 511A and MBBS 511B can be taken in any sequence. Restricted to consent of department. Special approval needed from the instructor.

Credit Hours: 4

This course provides content covering the drug development process and FDA regulatory requirements for over-the-counter and prescription drugs and biologics. It provides an overview of the drug development phases, the pharmaceutical industry, and the regulatory concepts that shape federal oversight and industry decisions. No prerequisites are required.

Credit Hours: 2

Advanced Human Neuroanatomy with Lab (4 hours) examines the detailed structure of the human nervous system, linking structure to function at both the clinical and neurobiological level. The overall objective of the course will be a three-dimensional understanding of nervous system structure and organization, based upon anatomical connections, functions, and diseases. Graduate students will engage in literature reviews relevant to course material and submit final projects as approved by course instructors. Enrollment requires consent of the instructor. Students who have passed PHSL 402 are not eligible for enrollment. Lab fee: $25.

Credit Hours: 4

Individualized laboratory research and training. Graded credit for Master's Degree only.

Credit Hours: 1-6

Individualized laboratory research and training. Graded credit for Master's Degree only.

Credit Hours: 1-6

Individualized laboratory research and training. Graded credit for Master's Degree only.

Credit Hours: 1-6

Individualized laboratory research and training. Graded credit for Master's Degree only.

Credit Hours: 1-6

Individualized laboratory research and training. Graded credit for Master's Degree only.

Credit Hours: 1-6

Individualized laboratory research and training. Graded credit for Master's Degree only. Enrollment requires approval of the instructor.

Credit Hours: 1-6

Individualized laboratory research and training. Graded credit for Master's Degree only.

Credit Hours: 1-6

A survey of the components of the immune system and how they interact with each other to produce responses that are important in the control or mediation of human disease. Three hours lecture. Restricted to consent of instructor.

Credit Hours: 3

The physiology, biochemistry and genetics of microbial regulatory mechanisms. Topics include transport phenomena, catabolite and nitrogen repression, the stringent response, and autoregulatory phenomena. Two lectures per week. Prerequisite: MBBS 425; or CHEM 451A and B, or consent of instructor.

Credit Hours: 2

A-B sequence. Advanced Clinical Anatomy provides students with a thorough understanding of human anatomy and its application to medicine. The course will encompass osteology, musculature, the circulatory system, viscera, the nervous system, and the medical implications of anatomy. This will be achieved through various approaches including demonstrations with prepared specimens, student dissections, anatomical models, case studies, online materials, medical imaging, lectures, guided study sessions, and independent learning. Enrollment by consent of instructor. Lab fee: $20.

Credit Hours: 5

A-B sequence. Advanced Clinical Anatomy provides students with a thorough understanding of human anatomy and its application to medicine. The course will encompass osteology, musculature, the circulatory system, viscera, the nervous system, and the medical implications of anatomy. This will be achieved through various approaches including demonstrations with prepared specimens, student dissections, anatomical models, case studies, online materials, medical imaging, lectures, guided study sessions, and independent learning. Enrollment by consent of instructor. Lab fee: $20.

Credit Hours: 5

This course will examine the molecular and cellular aspects of physiology in the context of human pituitary and neurological genetic disorders using the primary literature as the source of topics for oral presentations and discussions. Topics include experiments and model systems used to examine the regulation of gene expression, signaling pathways, protein activities, and cellular functions that underlie these disorders. Special approval needed from the instructor.

Credit Hours: 3

(This course will be offered in Springfield only). An advanced course based on current literature concerning the cellular biology of eukaryotes. Both students and faculty will make presentations followed by discussion. Topics will include: the cellular and subcellular structure and function of the lower eukaryotes, the biochemistry and biophysics of eukaryotic membrane systems and the higher subcellular functions of mammalian cells. Prerequisite: 400 level course in genetics and in biochemistry or consent of instructor.

Credit Hours: 3

Lecture course in molecular and cellular biological techniques used in the study of organisms; structures and processes involved in genome organization; packaging and replication of DNA; transcription and RNA processing; recombination and transposition of DNA; gene regulation with emphasis on developmental processes; signal transduction; structure and function of cellular components; cell-cell interaction; etc. Prerequisites: MBBS 554A and MBBS 554B or consent of instructor.

Credit Hours: 3

The goal of this course is to understand the process involved in scientific discovery and research by reading, analyzing, criticizing and discussing scientific articles covering the field of Pharmacology and Neuroscience and the related field of cellular and molecular biology. Prerequisites: MBBS 550A Principles of Pharmacology and MBBS 577 Neuroscience.

Credit Hours: 3

Lecture course in control mechanisms of biochemical processes, enzyme kinetics, regulation and allostery, coupled systems and energy transduction, membranes, transport, etc. Prerequisite: BCHM 451A or consent of instructor.

Credit Hours: 3

This course will provide information on topics relevant to the ethical conduct of research, including conflict of interest, publication policies, animal and human subjects, peer review, and mentoring. No prerequisite.

Credit Hours: 1

This course has a laboratory component of approximately 4-6 hours/week/credit hour of training in a functioning public health laboratory. The content of the course provides in-depth experience in the scientific basis and use of analytical methods in microbiology, immunology and molecular biology that are unique to public health laboratories at the state and national level. Prerequisite: MBBS 545.

Credit Hours: 3-9

This course has a laboratory component of approximately 4-6 hours/week/credit hour of training in a functioning public health laboratory. The content of the course provides in-depth experience in the scientific basis and use of analytical methods in environmental chemistry and biochemistry that are unique to public health laboratories at the state and national level. Prerequisite: MBBS 541A.

Credit Hours: 3-9

This course reviews introductory statistics and focuses on advanced statistics, linear and nonlinear modeling, applicable to basic bimedical sciences. The course will also provide students with experience in the use of statistical package computer programs for data analysis. No prerequisite required.

Credit Hours: 3

The scientific basis of current laboratory practice of public health science in the areas of microbiology, immunology, molecular biology, environmental chemistry, biochemistry and instrumentation (to accompany 541A,B). Prerequisite: MBBS 510, Bachelor's degree in Biology, Chemistry, Physical Science.

Credit Hours: 3

A study of chemistry, pharmacodynamic actions, mechanisms of action, absorption, distribution, metabolism, elimination, adverse effects, interactions and toxic effects of drugs currently used in therapeutics. Three to five hours lecture, one to four hours discussion per week. Must be taken in sequence. Prerequisite: MBBS 577 or instructor permission.

Credit Hours: 4

A study of chemistry, pharmacodynamic actions, mechanisms of action, absorption, distribution, metabolism, elimination, adverse effects, interactions and toxic effects of drugs currently used in therapeutics. Three to five hours lecture, one to four hours discussion per week. Must be taken in sequence. No prerequisite required.

Credit Hours: 4

The main objective is to acquaint the student with various sophisticated laboratory equipment, basic techniques/principles of pharmacological experiments. One hour lecture and three hours laboratory twice weekly. This course is prerequisite to all advanced pharmacology courses. (Springfield Only.)

Credit Hours: 4

A lecture-discussion course covering contemporary aspects of cellular immunology. The cellular nature of immune responses as well as current information on the regulation of such responses will be considered. Topics will include cellular components of an immune response; receptors, recognition and signals; cellular cooperation; immuno-regulation; and tolerance and autoreactivity. Prerequisites: MBBS 453 or MBBS 518 or consent of instructor.

Credit Hours: 3

First course of a two semester, comprehensive biochemistry course sequence. Introduction to structure and function of biomolecules including nucleic acids, proteins, sugars, polysaccharides, lipids and membranes, biochemical techniques, expression of genetic information, signal transduction and transport through membranes. Three lectures and one seminar per week. Seminar will consist of primary literature discussion and student presentation on areas covered in lecture. Principal lecturer for each of the area topics will lead discussion and assign the primary literature. Prerequisites: CHEM 340 or CHEM 442 or equivalents with a C- or better, or instructor permission. Students who have previously passed BCHM/CHEM 451A are not eligible to register for this course.

Credit Hours: 3

Second course of a two semester, comprehensive biochemistry course sequence. Basic kinetics, enzyme kinetics, enzyme inhibitors, regulation of enzymes, oxidation-reduction, high energy bonds, carbohydrate metabolism, aerobic/anaerobic metabolism, lipid metabolism, nitrogen metabolism, hormonal control of metabolism. Three lectures and one seminar per week. Seminar will consist of primary literature discussion and student presentation on areas covered in lecture. Principal lecturer will lead discussion and assign the primary literature. Prerequisites: CHEM 340 or CHEM 442 or equivalents with a C- or better, or instructor permission. Students who have previously passed BCHM/CHEM 451B are not eligible to register for this course.

Credit Hours: 3

This course explores the theories and practice of medicine from antiquity to present day by examining changing cultural norms and scientific understanding of the human body throughout history. The focus is on understanding the development of Western medicine, but medical practice in ancient and non-Western cultures will also be explored.

Credit Hours: 1-3

(Same as ANTH 556, PLB 556, ZOOL 556) An advanced introduction to modern methods of phylogenetic inference, emphasizing both theoretical background concepts and numerical approaches to data analysis. Topics include properties of morphological and molecular characters, models of character evolution, tree estimation procedures, and tree-based testing of evolutionary hypotheses. Special approval needed from the instructor.

Credit Hours: 3

A lecture-discussion course in molecular and cellular biology of tumor pathogenesis. The lecture covers various aspect of current tumor biology. The in-depth discussion on recent articles will provide students with opportunity to become familiar with front-line research in molecular oncology. Prerequisite: MBBS 554A or consent of instructor.

Credit Hours: 3

Discussion based course of selected topics in Anatomy & Neurobiology of current scientific interest to faculty and students.

Credit Hours: 1-6

Discussion based course of selected topics in Biochemistry & Molecular Biology of current scientific interest to faculty and students.

Credit Hours: 1-6

Discussion based course of selected topics in Cell Biology & Immunology of current scientific interest to faculty and students.

Credit Hours: 1-6

Discussion based course of selected topics in Cancer Biology of current scientific interest to faculty and students.

Credit Hours: 1-6

Discussion based course of selected topics in Medicinal Chemistry of current scientific interest to faculty and students.

Credit Hours: 1-6

Discussion based course of selected topics in Microbiology of current scientific interest to faculty and students.

Credit Hours: 1-6

Discussion based course of selected topics in Physiology of current scientific interest to faculty and students. Enrollment requires approval of the instructor.

Credit Hours: 1-6

Discussion based course of selected topics in Pharmacology & Neuroscience of current scientific interest to faculty and students.

Credit Hours: 1-6

This course provides basic neuroscience knowledge covering the fundamental principles of neural cell biology, neurophysiology, neurochemistry, neuroanatomy and behavior. This knowledge is essential to understand the mode of action of the drugs acting on excitable cells including muscle, autonomic system and central nervous system. No prerequisite.

Credit Hours: 4

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Enrollment requires approval of the instructor. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Letter grade.

Credit Hours: 1-6

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. Enrollment requires approval of the instructor. S/U grading.

Credit Hours: 1-12

Supervised readings for qualified graduate students. Special arrangements to be made with the instructor with whom the student wishes to work. S/U grading.

Credit Hours: 1-12

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work. Enrollment requires approval of the instructor.

Credit Hours: 1-24

Credit for conducting research. Special arrangements to be made with the instructor with whom the student wishes to work.

Credit Hours: 1-24

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Master's degree thesis.

Credit Hours: 1-6

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

Research for Ph.D. degree dissertation.

Credit Hours: 1-32

For those graduate students who have not finished their degree programs and who are in the process of working on their dissertation, thesis or research paper. The student must have completed a minimum of 24 hours of dissertation research, or the minimum thesis, or research hours before being eligible to register for this course. Concurrent enrollment in any other course is not permitted. Graded S/U or DEF only.

Credit Hours: 1